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Drug info
P R O B E
• V o l . L I I I • N o . 3 • A p r – J u n 2 0 1 4
–
–
UTI during pregnancy
–
–
Nonspecific urethritis
–
–
Nonspecific dysuria
–
–
Burning micturition
–
–
Hyperuricemia
Dosage
Urolithiasis and crystalluria (adult
and pediatric):
2 tablets twice
daily till the stone passes out, or till
symptoms subside.
Preventing recurrence after surgical
removal or passage of stone:
1 tablet
twice daily for 6 months.
Urinary tract infections including
recurrent UTI:
1 tablet twice daily
until the infection is cleared.
To prevent recurrent UTI, recommend
Cystone along with antibiotic therapy
and continue for at least 3 weeks.
Burning micturition:
1 tablet twice
daily till the symptoms subside.
Dosage may be titrated depending
on the severity and chronicity of the
disease.
Adverse Effects
No adverse effects have been reported.
Contraindications
No known contraindications.
Special Precautions
In complete ureter obstruction, it is
advisable not to recommend Cystone
tablet.
Drug Interactions
No clinically or biochemically
significant drug interactions have been
reported
Presentation
Sealed packs of 60 tablets
Pharmacological
Actions of Principal
Ingredients
1. Antilithiatic and
lithotriptic actions
Cystone tablet exhibits antilithiatic
action that helps to prevent the
deposition, accumulation, and
supersaturation of calculogenic
chemicals in urine. It inhibits
calculogenesis and corrects the
crystalloid–colloid imbalance.
Cystone tablet possesses lithotriptic
action that dissolves the mucin that
binds stone particles.
D pedicellata
,
D biflorus
,
S ligulata
,
T terrestris
, and
E arvense
prevent
the deposition, accumulation, and
supersaturation of calculogenic
chemicals in urine. Hajrul yahood
bhasma has lithotriptic property.
R cordifolia
has ruberythric acid,
which dissolves oxalate stones
present in the urinary tract, thereby
facilitating their expulsion without
recourse to surgery.
2. pH-renormalizing action
Cystone tablet renormalizes the
urinary pH and relieves burning
micturition.
E arvense
renormalizes and maintains
the urinary pH within the alkaline
range, that is, from 7.5 to 8.0.
3. Diuretic action
Cystone tablet offers diuretic action
and flushes out small stones and
gravels.
D pedicellata
,
S ligulata
,
A aspera
,
O bracteatum
,
T grandis
, and Hajrul
yahood bhasma have potent diuretic
actions.
C scariosus
exhibits diuretic activity
and is also useful in maintaining
genitourinary health.
4. Antimicrobial action
Cystone tablet has broad antimicrobial
action against common urinary
pathogens.
S ligulata
,
R cordifolia
,
O basilicum
,
T terrestris
, and
E arvense
have broad-
spectrum antimicrobial actions
against common urinary pathogens
responsible for recurrent UTI.
5. Anti-adherent action
Polyphenols present in Cystone syrup
are known to act as natural anti-
adhesion components responsible for
preventing the adhesion of
Escherichia
coli
to the uroepithelium. This helps in
natural evacuation of
E coli
along with
the urine flow.
6. Anti-inflammatory action
C scariosus
,
R cordifolia
,
V cinerea
,
Shilajeet (purified),
O basilicum
,
E arvense
, and
S ligulata
have anti-
inflammatory activities.
7. Demulcent action
S ligulata
and
P odorata
have
demulcent properties due to high
content of mucilage and soothe and
protect the irritated or inflamed
internal tissues.
O bracteatum
, a demulcent, is useful
for the treatment of bladder irritation
and retention of urine.
8. Spasmolytic action
Cystone tablet exhibits spasmolytic
activity and relieves renal colic.
O bracteatum
is a powerful
antispasmodic agent.
9. Antioxidant action
R cordifolia
,
O basilicum
,
E arvense
,
and
T grandis
are strong antioxidant
agents.
10. Tonic action
Cystone tablet has tonic property that
improves and tones the urinary tract.
Tonic activity of Shilajeet (purified)
helps in the treatment of urinary
disorders. Tonic activity of
C scariosus
is useful for maintaining
genitourinary health.
