38
Abstracts
P R O B E
• V o l . L I I I • N o . 3 • A p r – J u n 2 0 1 4
Gynecology
Calcium and Vitamin D Supplementation
and Risk of Kidney Stone Formation in
Postmenopausal Women
Haghighi A, et al
Iran J Kidney Dis
. 2013;7(3):210–213.
This study aimed to compare the metabolic changes after
supplementation of calcium and vitamin D and examine
the risk of stone formation.
Fifty-three postmenopausal women referred to
rheumatology clinic, who had no history of kidney
calculi, bone diseases (apart from osteoporosis), metabolic,
and rheumatic disorders and had not been receiving
calcium, diuretics, and calcitonin were investigated. Renal
ultrasonography and blood tests were performed and the
urine calcium levels were measured for a period of 24 hours
for all patients. The examinations were repeated after a
1 year of treatment with supplemental calcium (100 mg/d)
and vitamin D (400 IU/d) and compared with the data
before the treatment.
After 1 year, asymptomatic urolithiasis was confirmed in 1
of 53 patients (1.9%) using ultrasonographic examination.
No significant differences were found between the 24-hour
urine and blood calcium levels before and after the
treatment.
Our findings showed that oral intake of calcium and
vitamin D after 1 year has no effect on the urinary calcium
excretion rate and the formation of kidney calculi in
postmenopausal women.
Natural History of Irritable Bowel Syndrome in
Women and Dysmenorrhea: A 10-year Follow-
up Study
Olafsdottir LB, et al
Gastroenterol Res Pract
. 2012;2012:534204.
Studies have shown that women are more likely to have
irritable bowel syndrome (IBS) and more women seek
healthcare because of IBS than men.
We wanted to examine the natural history of IBS and
dysmenorrhea in women over a 10-year period and to assess
the change in IBS after menopause.
Seventy-seven percent premenopausal women had
dysmenorrhea in the year 1996 and 74% in 2006.
Forty-two percent of women with dysmenorrhea had IBS
according to Manning criteria in the year 2006 and 49%
in 1996. 26% of women with dysmenorrhea had IBS
according to Rome III 2006 and 11% in the year 1996. In
2006, 30% women had severe or very severe dysmenorrhea
pain severity. More women (27%) reported severe
abdominal pain after menopause than before menopause
(11%). Women without dysmenorrhea were twice more
likely to remain asymptomatic than the women with
dysmenorrhea. Women with dysmenorrhea were more likely
to have stable symptoms and were twice more likely to have
increased symptoms.
Women with IBS are more likely to experience
dysmenorrhea than women without IBS which seems to be
a part of the symptomatology in most women with IBS. IBS
symptom severity seems to increase after menopause.
