10 Vet Info-H • Sep–Dec 2023 • Vol 11 • No. 4 Research at Himalaya Mobility Plus® (TABLET) Mobility Plus is a unique blend of herbal ingredients that support optimal bone and joint health. The herbs present in Mobility Plus possess anti-inflammatory, chondroprotective, anti-arthritic, and analgesic properties. Assessment of Anti-inflammatory, Anti-arthritic, and Analgesic Properties of Mobility Plus® Tablet Aim To assess the anti-inflammatory, anti-arthritic, and analgesic effects of Mobility Plus in dogs with arthritis, hip dysplasia, and pain in the joints Materials and Methods In this study, 31 client-owned dogs (of both sex; age range, 5-10 y ) suffering from arthritis, hip dysplasia, and pain in the joints were included. For the initial 6 weeks, the dogs of large breeds were prescribed 2 tablets of Mobility Plus per day, and the dogs of small breeds were prescribed 1 tablet of Mobility Plus per day. After completing the course in 6 weeks, the dogs of large breeds were prescribed 1 tablet of Mobility Plus per day, and the dogs of small breeds were prescribed ½ tablet of Mobility Plus per day, until complete recovery. No other analgesic, antipyretic, and anti-inflammatory medications were given to these dogs during this treatment. The dogs were evaluated for joint mobility, pain, lameness, and weight-bearing scores. Results After 15 days of treatment with Mobility Plus, there was an improvement in the assessment parameters (ie, joint mobility, pain, lameness, and weight-bearing scores), and they further improved significantly (P < .001) by day 30, 45, and 60, gradually. The overall clinical condition score started to decrease as early as day 15 and significantly (P < .001) decreased by day 30, 45, and 60. However, the complete amelioration of joint mobility, pain, lameness, and weight-bearing ability was observed by day 60 (Table). Table. Effect of Mobility Plus on the Assessment Parameters in Dogs Parameter Initial Day 15 Day 30 Day 45 Day 60 Lameness Score 4.84 ± 0.08 4.48 ± 0.15 a3.90 ± 0.20 a3.71 ± 0.22 a3.35 ± 0.26 Joint Mobility Score 4.55 ± 0.13 4.26 ± 0.15 a3.65 ± 0.21 a3.42 ± 0.22 a3.29 ± 0.25 Pain Score 4.00 ± 0.22 3.81 ± 0.19 a3.16 ± 0.19 a3.00 ± 0.22 a2.81 ± 0.20 WeightBearing Score 3.74 ± 0.25 3.35 ± 0.23 a2.77 ± 0.19 a2.71 ± 0.20 a2.55 ± 0.17 Overall Clinical Condition Score 3.23 ± 0.28 3.00 ± 0.27 a2.52 ± 0.23 a2.45 ± 0.19 a2.19 ± 0.16 Values are expressed as mean ± SEM (N = 31). aP < .001 compared with day 0 based on repeated measures two-way ANOVA followed by the Bonferroni test. Discussion and Conclusion Mobility Plus, a polyherbal formulation developed by Himalaya Wellness Company, comprises potential herbs such as Zingiber officinale, Persea americana, Glycine max, Ananas comosus, and Commiphora wightii. The study results showed that the improvement in the clinical condition of the dogs is ascribed to the antiinflammatory, anti-arthritic, and analgesic properties of the herbs present in Mobility Plus. Source: Ashwath KC, et al. Indian J Anim Res. August 24, 2021 (doi: 10.18805/IJAR.B-4521).
RkJQdWJsaXNoZXIy MjAwNDg=