T h e r a p e u t i c I n d e x 46 Cystone® forte (tablet) Expels kidney stones and prevents recurrence Cystone forte tablet, an Ayurvedic proprietary formulation, is recommended for the comprehensive management of urolithiasis and urinary tract infections (UTIs). Cystone forte tablet helps in the management of large stones and relieves associated obstructive symptoms (such as frequency of micturition, hematuria, and pain) and postlithotripsy complications (which further helps reduce the number of lithotripsy sessions). Composition Each Cystone forte tablet contains: Exts. Shilapushpa (Didymocarpus pedicellata)........ 195 mg Pashanabheda (Saxifraga ligulata). .................. 147 mg Manjishtha (Rubia cordifolia). ................................48 mg Nagaramusta (Cyperus scariosus). ........................48 mg Apamarga (Achyranthes aspera). ..........................48 mg Gojihva (Onosma bracteatum)...............................48 mg Sahadevi (Vernonia cinerea). ..................................48 mg Pdrs. Shilajeet (Purified). ....................................................39 mg Hajrul yahood bhasma.............................................48 mg Clinical Pharmacology Cystone forte tablet has antilithiatic, lithotriptic, pH-renormalizing, diuretic, antimicrobial, antiadherent, antiinflammatory, demulcent, spasmolytic, antioxidant, and tonic actions. The antilithiatic action of Cystone forte tablet prevents the deposition, accumulation, and supersaturation of calculogenic chemicals in urine. Cystone forte tablet controls oxamide absorption from the intestine; corrects the crystalloid–colloid imbalance; and inhibits calculogenesis by reducing the levels of stone-forming substances such as oxalic acid and calcium hydroxyproline. The lithotriptic action of Cystone forte tablet helps in the dissolution of the calculi. Cystone forte tablet causes disintegration of the calculi and crystals by acting on the mucin that binds the particles together. Cystone forte tablet possesses diuretic action and flushes small stones from the urinary tract. The pH-renormalizing action of Cystone forte tablet brings about a cooling effect on the urinary system and relieves burning micturition. Cystone forte tablet exerts antimicrobial action against the common urinary pathogens responsible for recurrent UTIs. Cystone forte tablet prevents the adhesion of Escherichia coli to the uroepithelium, which helps reduce the adhesion of Escherichia coli to the cells lining the urinary tract and promotes its expulsion along with the natural flow of urine. Processed in Vanatulasi (Ocimum basilicum), Gokshura (Tribulus terrestris), Lajjalu (Mimosa pudica), Kulattha (Dolichos biflorus), Balam (Pavonia odorata), Joratoota (Equisetum arvense), and Shaka (Tectona grandis).
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