T h e r a p e u t i c I n d e x 39 Composition Each 5 mL of Cystone syrup contains: Exts. Pdrs. Gokshura (Tribulus terrestris).................................91 mg Saindhava................................................................... 50 mg Punarnava (Boerhaavia diffusa)............................67 mg Suvarchika...............................................................42.5 mg Pashanabheda (Saxifraga ligulata)......................53 mg Yavakshara. ...................................................................5 mg Mustaka (Cyperus rotundus)...................................42 mg Narasara..................................................................... 2.5 mg Shatavari (Asparagus racemosus).........................21 mg Kulattha (Dolichos biflorus). ...................................21 mg Ushira (Vetiveria zizanioides). ................................21 mg Trikatu............................................................................20 mg Karchura (Curcuma zedoaria)................................14 mg Clinical Pharmacology Cystone syrup has antilithiatic and lithotriptic, pH-renormalizing, diuretic, antimicrobial, anti-adherent, anti-inflammatory, spasmolytic, and antioxidant actions along with bioavailability-enhancing property. The antilithiatic action of Cystone prevents the deposition, accumulation, and supersaturation of calculogenic chemicals in urine. Cystone also controls oxamide absorption from the intestine. Cystone corrects the crystalloid–colloid imbalance. Cystone inhibits calculogenesis by reducing stone-forming substances like oxalic acid and calcium hydroxyproline. The lithotriptic action of Cystone helps in the dissolution of calculi. Cystone causes disintegration of the calculi and crystals by acting on the mucin that binds the particles together. Cystone offers diuretic action and flushes small stones from the urinary tract. The pH-renormalizing action of Cystone provides cooling action in the urinary system and relieves burning micturition. Cystone provides antimicrobial action against common urinary pathogens responsible for recurrent UTI. Cystone is proven by a radiolabeled biotech assay to prevent the adhesion of Escherichia coli to the uroepithelium. This action helps in reducing the adhesion of Escherichia coli to the cells lining the urinary tract and promotes the expulsion of Escherichia coli along with the natural flow of urine. Cystone® (syrup) The natural choice in UTI Cystone syrup, an Ayurvedic proprietary formulation, is recommended for the comprehensive management of urolithiasis and urinary tract infections (UTI). Cystone syrup expels kidney stones and ureteric stones, and prevents their recurrence. Cystone syrup is safe and effective in the management of pediatric urolithiasis and UTI, and causes significant reduction of associated symptoms.
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