Therapeutic Index

T h e r a p e u t i c I n d e x 28 Composition Each mL of Bresol-NS saline nasal solution contains: Exts. Yashtimadhu (Glycyrrhiza glabra)..................... 0.25 mg Parnayavani (Coleus aromaticus)...................... 0.10 mg Oils Tailaparna (Eucalyptus globulus).....................0.075 mg Also contains sodium chloride IP 0.65% w/v as a base Clinical Pharmacology Bresol-NS saline nasal solution is an Ayurvedic proprietary formulation with 100% natural active ingredients with demulcent, anti-inflammatory, antimicrobial, local analgesic, and anti-allergic actions. Bresol-NS helps keep the nasal mucosa moist, softens the mucous crusts, clears the built up tenacious mucus, and helps wash off allergens. The demulcent, anti-inflammatory, and anti-allergic actions of Bresol-NS help soothe the irritated and swollen mucosa by reducing inflammation, strengthening natural defense, and relieving nasal congestion. Bresol-NS helps physically disrupt the viscous surface layer of the nasal mucosa; removes the thick mucus, crusts, and debris; and rinses off airborne aggressors (eg, pollutants, pollen, and microorganisms). The saline nature of the solution helps pull water out of the cells, resulting in increased hydration of the deeper aqueous portion of the mucous layer. This improves mucociliary clearance, reduces local inflammatory mediators, and thus, decreases nasal epithelial edema. Indications • Nasal congestion caused by – Allergy – Upper respiratory tract infections (URTIs) – Nasal polyp Bresol®-NS Saline Nasal Solution (drops/spray) Breathing solution for a dry and stuffy nose Bresol-NS is a saline-based nasal drops/spray with the advantage of herbal ingredients. Bresol-NS is useful in the management of nasal congestion associated with allergies and upper respiratory tract infections. Bresol-NS is nonstaining, nonaddictive, free from artificial colors and fragrance, and clinically tested for safety and efficacy.

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