Therapeutic Index

T h e r a p e u t i c I n d e x 236 Rubia cordifolia has antibacterial property. Moringa pterygosperma possesses antibacterial and antiviral properties and inhibits the growth of gram-positive and gram-negative bacteria such as Escherichia coli, Salmonella typhi, and Salmonella paratyphi. The roots of Inula racemosa have antimicrobial activity. 3. Host response–modulating action: Tinospora cordifolia is known to increase antibody levels and activate macrophages. Emblica officinalis enhances cell survival and increases phagocytosis and IFN-γ production. Glycyrrhizin from Glycyrrhiza glabra potentiates the reticuloendothelial system and acts on macrophage function in vitro, leading to stimulation of macrophages de novo. β-Glycyrrhetinic acid from Glycyrrhiza glabra is a potent inhibitor of the classical complement pathway. 4. Antioxidant action: Commiphora wightii, Rubia cordifolia, Emblica officinalis, Glycyrrhiza glabra, and Moringa pterygosperma have potent antioxidant action. 5. Other beneficial activities: Tinospora cordifolia and Emblica officinalis possess antipyretic property. Commiphora wightii is beneficial in respiratory tract infections including chronic tonsillitis, pharyngitis, chronic bronchitis, nasal catarrh, and laryngitis. Glycyrrhiza glabra is an expectorant, beneficial in asthma, acute or chronic bronchitis, and chronic cough. Shankha bhasma is commonly used in Ayurveda for the treatment of dyspepsia/indigestion. The antioxidant activity of Shankha bhasma modulates free radical scavenging and helps protect the gastric lining. Septilin® (syrup, tablet)

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