Probe • Vol LXII • No. 4 • Sep–Dec 2023 • 9 Pilex in the Management of External and Internal Hemorrhoids had internal hemorrhoids, and 9 patients had both internal and external hemorrhoids. • The patients received 1 Pilex Tablet, BID, for 6 weeks. • Proctoscopic examination was done before treatment and at every fortnightly follow-up during the treatment period. • The patients were evaluated for the reduction in the size of the hemorrhoidal mass, pain during defecation, bleeding during defecation, anal pruritus, strenuous bowel movements, and loss of appetite. • At the end of the study, the efficacy of the treatment was recorded as either very good, good, or not effective, based on a 4-point scale. • A significant reduction in the symptoms of hemorrhoids such as pain and bleeding was observed during the follow-ups. • The treatment response was very good in 56.25% of the patients and good in 37.50% of the patients. • No side effects were observed during the study. • The results demonstrate that Pilex Tablets are safe and effective in the treatment and management of mild-to-moderate internal and external hemorrhoids. Clinical Evidence 2 Efficacy of Pilex® in the Treatment and Management of Advanced Degrees of Hemorrhoids Aim To evaluate the efficacy of Pilex Tablets in the treatment and management of advanced degrees of hemorrhoids Materials and Methods This clinical study enrolled 11 patients, of whom 4 patients had third-degree hemorrhoids, and 7 patients had fourth-degree hemorrhoids. The duration of hemorrhoids in the patients varied from 3 months to 8 years. Prior to the study, the patients were operated upon for associated conditions such as acute retention of urine (due to benign prostatic hyperplasia), acute intestinal obstruction, perforated peptic ulcer, and obstructed inguinal hernia. Suprapubic transvesical prostatectomy was performed on patients with prostatic hypertrophy. Exploratory laparotomy was performed on patients with acute intestinal obstruction and perforated peptic ulcer for a simple closure of the perforation and release of the obstruction. The remaining patients were operated for hernia. Sphincter dilation of the anal canal was performed immediately after their respective surgical procedures. While still under the effect of anesthesia, the patients were turned to their left side and had their knees drawn up. The whole anal canal and lower rectum were slowly and uniformly dilated. Tight bands were broken down and irregularities in the anal canal were ironed out. The anal canal was then lightly packed with paraffin gauze to prevent prolapse of hemorrhoids. Pilex treatment was started 3 to 5 days after the surgery and sphincter dilation. The patients received 2 tablets of Pilex, TID, for 4 to 6 weeks. The patients also received an ounce of liquid paraffin at bedtime. After discharge, the patients were followed up
RkJQdWJsaXNoZXIy MjAwNDg=